Short-term memory in children with sickle cell disease: executive versus modality-specific processing deficits.

Patterns of verbal long-term and working memory performance reveal deficits in strategic processing in children with frontal infarcts related to sickle cell disease.

Frontal brain regions are thought to mediate strategic processes that facilitate memory. We hypothesized that children with frontal cerebral infarcts related to sickle cell disease (SCD) would exhibit impairments in long-term and working memory as a result of disruptions in strategic processing. Word-list learning and digit span tasks were used to assess verbal memory and strategic processing i...

Effects of exercise on spatial memory deficits induced by nucleus basalis magnocellularis lesions

Introduction: Previous studies have shown that exercise enhances cognitive and functional capacities in patients with Alzheimer's disease (AD). In this study, we investigated the effect of long-term (60 days) and short- term (10 days) exercise on the spatial memory deficits in an animal model of AD. Methods: Fifty male rats were divided into 5 groups 1) intact, 2) sham, 3) sham-Alzheimer 4) ...

P58: Visual Working Memory Performance Based on Saccades in Children with and without Specific Learning Disorder: An Eye-Tracking Study

Some of the previous studies show that children with SLD have deficits in visual processing and working memory. Hence, the aim of this research was to investigate problems of visual working memory based on behavioral neuroscience method, using an eye tracker device. The method of present study was ex-post facto study. The participants included couple of twelve children with SLD (mean age=10.92)...

The Association of Cytokine Levels With Cognitive Function in Children With Sickle Cell Disease and Normal MRI Studies of the Brain.

Children with sickle cell disease, including those without evidence for cerebral infarcts, are at increased risk for cognitive deficits that can contribute to difficulties in academic and social functioning. Chronic inflammatory processes are endemic to sickle cell disease and are apparent in common comorbidities including asthma. Cytokines mediating inflammatory processes can influence cogniti...

Working Memory in Children with Neurocognitive Effects from Sickle Cell Disease: Contributions of the Central Executive And Processing Efficiency